By Donald
B. Ardell – March 14, 2010
Researchers
at King's College in London found that people who exercise have longer
telomeres, a marker for biological age. Telomeres are essential functional elements of eukaryotic chromosomes
involved in genome stability maintenance. They are found at the end of a linear
chromosome. They tend to shorten over time. The length of telomeres is the same in youth for those who
do and those who do not exercise; however, by the middle years, only fit
people, those who have exercised regularly, have long telomeres consistent with
lengths noted in the young. Thus,
the study indicates regular exercise and attendant high fitness levels later in
life slow the aging process.
The King's
College researchers emphasized that the relationship between telomere length
and physical activity levels remained significant even after adjustments were
made for such variables as body mass index, smoking, socioeconomic status and
physical activity at work.
Amby
Burfoot, writing for Peak Performance (A Telling Tale of Telomeres, Exercise,
Health, and Aging, February 15, 2010), quotes University of Colorado runner,
coach and telomere expert Tom LaRocca on the significance of these studies:
“Telomeres are structures at the ends of human chromosomes that protect DNA
from damage. To help you visualize them, they are often compared to the little
plastic tips at the ends of shoelaces. As cells age and replicate, their
telomeres shorten. When telomeres become critically short, cells stop
functioning properly. So, the general idea is that telomeres may be a
'biological clock' that reflects your physiological age/health more accurately
than your chronological age. In other words, the longer the telomeres, the
healthier the cells. Hence, all the 'buzz' (including a recent Nobel Prize)
over telomeres.”
I have an
idea for linking these findings with wellness programs for the purpose of
motivating males who need to exercise more. It involves appealing to their vanity, and even exploiting
one of the foolish characteristics of the male psyche for this noble purpose.
This is
not to imply that ends justify means, but it kind of helps a bit in this
instance. The idea is simple but quite possibly ingenious, if I say so myself:
Design ways to get guys to jettison their jejune fixation on penis size in
favor of pride in the length of their telomeres. Naturally, this is not the
greatest reason to exercise but, hey, if it gets some doing the right thing for
the wrong reasons, it's still positive.
A
telomere-focused penile-replacement virility symbol of male self-concept could
be employed as an appealing fitness and motivational strategy - for guys. The President's Council on Physical
Fitness and Sports (PCPF&S) could become the certifying national focal
point for the program. The Council
could monitor testing at approved sites across the land and make test scores
official, with suitable recognition awards. Approved sites might include fitness centers, country clubs,
massage parlors, medical clinics, drug stores and so on.
Just as
cats can be skinned in varied ways (does anyone do that anymore?), so, too can
telomere ends be measured. Various approaches are used for this purpose. One of the latest techniques is called
flow cytometry. This method uses
fluorescence in situ hybridization (flow FISH) with labeled peptide nucleic
acid (PNA) probes. (No, I have no idea what this means, either.) But I do know that flow cytometry measures
the average length of telomere repeats at chromosome ends in individual cells -
and that's what's crucial to my plan.
If this
information is marketed properly by wellness promoters and other fitness
experts, guys will be motivated to have their telomere lengths certified. Unfortunately, telomere lengths are not
a visible component of the impressive nature of any guy's studly assets, so
something else, a badge or article of clothing, should be considered.
Maybe
doctors or lab personnel could be authorized to issue beanie caps or official
telomere running shorts that would be color-coded by telomere length.
The
PCPF&S already has a product line companies can purchase to reward good
behavior, that is, employee exercise at worthy levels. The PCPF&S motivational products
include varied physical fitness awards, apparel, magnets, bumper stickers, pedometers
and teaching aids.
With my
plan, I believe middle age and older guys can be inspired by wellness promoters
and others to exercise more in order to show selected others that their
telomere ends measure up to the highest standards - and everyone will know what
that means.
Is this a
good idea or what? Be well.
Don Ardell
is the Well Infidel. He favors
evidence over faith, reason over revelation and meaning and purpose over
spirituality. His enthusiasm for
reason, exuberance and liberty are reflected in his books (14), newsletter (525
editions of a weekly report) and lectures across North America and a dozen other
countries.